1. The first thing you do is instantiate a Persister object.

2. Persisters isolated from a great number of patients (60–80%) after treatment with antibiotics had an atypical form.

3. Arietis bridges an important gap in antimicrobial drug discovery and technology development by identifying and developing compounds to kill “persister” cells

4. However, even the best Bactericidal antibiotics have limited efficacy against dormant persister cells, specialized survivors that are phenotypic variants of the wild type (1, 2).Bactericidal antibiotics from each of the three main classes have unique mechanisms of killing.